Is hair loss linked to prostate cancer?

Submitted by Regrowth.com Webmaster on Tue, Jul 20, 2010.

Does your hair loss make you more or less susceptible? This study of 938 men answered that question and the results may surprise you.

Finally some good news for the balding male.

Not only does he have to deal with the prospective loss of his hair, but also potential health risks. A correlation with heart disease has been made in several studies.

Now there is some good news for balding men. A recently published study of 938 men compared hair loss pattern, age balding began and other factors to determine any links.

They not only found that the two were not related, but men who bald younger may have less of a risk for prostate cancer.

See the study below.

Androgenic alopecia is not useful as an indicator of men at high risk of prostate cancer.

Eur J Cancer. 2010 Jun 17
Cremers RG, Aben KK, Vermeulen SH, den Heijer M, van Oort IM, Kiemeney LA.
Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, The Netherlands.

BACKGROUND: Androgens are assumed to play a central role in the pathophysiology of both prostate cancer (PC) and androgenic alopecia (AA). A correlation between the two phenotypes may be relevant for identification of men at high risk of PC. We evaluated the association between AA at different ages and PC in a large case-control study.

METHODS: The case group comprised 938 PC patients recruited from a population-based cancer registry. The controls (n=2160) were a random sample of the male general population. All subjects completed a questionnaire on risk factors for cancer, including questions on hair pattern at different ages using an adapted version of the Hamilton-Norwood scale, race and family history of PC. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable logistic regression.

RESULTS: Baldness at early age appeared to be associated with a lower risk of PC (baldness at age 20: OR=0.86; 95% CI 0.69-1.07 and baldness at age 40: OR=0.81; 95% CI 0.70-0.96). Baldness at completion of the questionnaire was not associated with PC: OR=1.10; 95% CI 0.89-1.34. An isolated 'frontal baldness' or 'vertex baldness' pattern was not significantly associated with PC at any age. Presence of a combined 'frontal and vertex' baldness pattern at age 40 was associated with a decreased risk of PC (OR=0.62; 95% CI 0.45-0.86). There were no significant associations between AA and aggressive PC.

CONCLUSIONS: We did not find consistent positive associations between AA at different ages and PC. Surprisingly, if anything, baldness at early age is inversely related to PC in this study. Androgenic alopecia is not useful as an indicator of men at high risk of PC. Copyright © 2010 Elsevier Ltd. All rights reserved.

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