Hairloss Study Abstract: Five-year follow-up of patients with benign prostatic hyperplasia treated with finasteride.
Title
Five-year follow-up of patients with benign prostatic hyperplasia treated with
finasteride.
Author
Geller J
Address
Mercy Hospital and Medical Center, San Diego, CA 92103-2180, USA.
Source
Eur Urol, 27: 4, 1995, 267-73
Abstract
In 18 of 55 original patients who completed 5 years of treatment with finasteride,
significant reductions in prostate size were noted at 1 year and sustained thereafter.
Symptom scores in these same patients were significantly improved or stable over the 5
years while maximal urinary flow rates were unchanged. Data from 15 of 18 other patients
who dropped out of the study before 5 years showed changes in prostate size, symptom score
and flow rates that were similar to those noted in patients treated for 5 years. No side
effects were noted in this study except for sexual dysfunction, which occurred in less
than 5% of the patients. With few exceptions, finasteride appears to arrest the process of
BPH over a 5 year period as indicated by sustained reductions in prostate size accompanied
by either symptomatic improvement or stability in all other patients.